Single nucleotide polymorphisms and recombination rate in humans :: Biology Genetic Diversity

Humans have numerous of the same elements but also a lot of constituenttic var.. Therefore, constituent sequencing is different in every whizz. This transmitted variation determines a persons eye color, sensory hair color, and other traits. However, this is also why some mountain get diseases and others dont. In a chromosome, the distance from the centromere dictates the rate of recombination. There is less make in the area around the centromere, so that leads to less variation. However, understanding variation is necessary in order to determine abnormal genes. A individual(a) gene is the basis for identifying the abnormality. By looking at non-random sites with gene differentiations, one can determine the gene that causes the disease. There is more variation in regions with recombination, which happens in meiosis. The rate at which the crossing over occurs varies, and this affects the variation present. shamble is not the only determinant for variation in a gene. pick als o plays a role. For role model, A gene is superior to B gene. C gene is connected to A gene through hereditary hitchhiking. If A gene is selected over B gene, C gene is also denotative frequently. This is known as genetic hitchhiking. A biological application of this is the malaria gene. The colorblindness gene is hitchhiked onto the malaria disgusting gene. Therefore, when a person drives the malaria resistant gene they also receive the colorblindness gene. As a result, colorblindness occurs more frequently in places where malaria is affluent because the people who dont receive the malaria resistant gene die and the people who are resistant and colorblind live and pass on their genes.ImplicationsThe main implication of this experiment is that study the differences in the various genotypes of humans can illustrate genetic diseases. For example if a subject has a certain genetic disease, this paper states that you could equality the afflicted subjects genome to an unaffiliated persons genome and determine the post of the disease on the chromosome. If the location of genetic diseases are found then it is conceivable to screen foetuses for genetic diseases. This brings up ethical issues, would you want to know if your child has an incurable genetic disease? If genetic diseases are detected in a fetus then it may be possible to someday perform gene therapy. Gene therapy is the treatment of a genetic disease by providing patients with cells containing guiltless and functional alleles for genes that are nonfunctional in their bodies.